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THE PREVENTIVE EFFECT OF COMMERCIALLY AVAILABLE ANTICARIOGENIC PRODUCTS ON ENAMEL EROSION INDUCED BY CARBONATED BEVERAGE IN VITRO

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Àå±âÅà( Jang Ki-Taeg ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç ¹× Ä¡Çבּ¸¼Ò
±èÁ¾Ã¶ ( Kim Chong-Chul ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç ¹× Ä¡Çבּ¸¼Ò
ÇѼ¼Çö ( Hahn Se-Hyun ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç ¹× Ä¡Çבּ¸¼Ò
ÀÌ»óÈÆ ( Lee Sang-Hoon ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç ¹× Ä¡Çבּ¸¼Ò

Abstract

º» ¿¬±¸´Â Ç׿ì½Ä Á¦Ç°ÀÎ Casein phosphopeptide-amorphous calcium phosphate(CPP-ACP)¸¦ Æ÷ÇÔÇÏ´Â Ä¡¾ÆÅ©¸², ºÒ¼Ò ¹Ù´Ï½¬, Àú³óµµ ºÒ¼Ò ¾çÄ¡¾×À» Ä¡¾Æ¿¡ µµÆ÷ÇÏ´Â °ÍÀÌ ´Ü½Ã°£ ź»êÀ½·á¿¡ ÀÇÇÑ ¹ý¶ûÁúÀÇ Ä§½ÄÀ» ¿¹¹æÇÒ ¼ö ÀÖ´ÂÁö »ìÆ캸±â À§ÇØ °èȹµÇ¾ú´Ù. ¹ý¶ûÁú ½ÃÆí¿¡ ´ÙÀ½°ú °°Àº Ç׿ì½Ä Á¦Ç°À» µµÆ÷ÇÏ¿´°í, ÀΰøŸ¾×¿¡ 24½Ã°£ º¸°üÇÑ ÈÄ, ÄÝ¶ó¿¡ 1ºÐ Áõ·ù¼ö¿¡ 1ºÐ¾¿ 5ȸ ¹ø°¥¾Æ ó¸®ÇÏ¿´´Ù. 1±º: ´ëÁ¶±º(¹«Ã³Ä¡) 2±º: CPP-ACP Ä¡¾ÆÅ©¸²±º 3±º: ºÒ¼Ò ¹Ù´Ï½¬±º(1,000 ppm F) 4±º: Àú³óµµ ºÒ¼Ò ¾çÄ¡¾×±º(227 ppm F) 5±º: ºÒ¼Ò ¹Ù´Ï½¬ + CPP-ACP Ä¡¾ÆÅ©¸²±º 6±º: Àú³óµµ ºÒ¼Ò ¾çÄ¡¾× + CPP-ACP Ä¡¾ÆÅ©¸²±º ¹Ì¼¼°æµµ¿Í ħ½Ä±íÀ̸¦ ÃøÁ¤ÇÏ¿´°í, Quantitative light-induced fluorescence(QLF)¸¦ ÀÌ¿ëÇÏ¿© ¾ÈÁ¤µÈ Çü±¤ °ÝÀÚ¿¡ ´ëÇÑ ºÎÇÇ Çü±¤ º¯È­ÀÎ ¥ÄQ¸¦ ÃøÁ¤ÇÏ¿© ¹«±âÁú °¨¼Ò·®À» Æò°¡ÇÏ¿´´Ù. 6ÀÏ µ¿¾È ½ÇÇèÀ» ¹Ýº¹ÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù. 1. ¹Ì¼¼°æµµ´Â 1±º¡Â2±º¡Â4±º<6±º<3±º¡Ö5±º ¼øÀ̾ú´Ù. 2. Æò±Õ ħ½Ä±íÀÌ´Â 5±º¡Ö3±º<6±º<4±º¡Ö2±º¡Ö1±º ¼øÀ̾ú´Ù. 3. ¥ÄQ´Â 1±º¡Ö2±º¡Â4±º¡Â6±º¡Â3±º¡Ö5±º ¼øÀ̾ú´Ù. ¥ÄQÀÇ °¨¼ÒÀ²Àº 1±º°ú 2±º, 4±º°ú 6±º, 3±º°ú 5±ºÀÌ °¢°¢ À¯»çÇÏ¿´´Ù. 4. ¥ÄQ´Â ¹Ì¼¼°æµµ¿Í °­ÇÑ ¾çÀÇ »ó°ü°ü°è¸¦ ³ªÅ¸³Â°í(r=0.96, p<0.05), ħ½Ä±íÀÌ¿Í´Â °­ÇÑ À½ÀÇ »ó°ü°ü°è¸¦ º¸¿´´Ù(r=-0.96, p<0.05).

The aim of this study was to evaluate the preventive effect of commercially available anticariogenic products, specifically, the tooth cream containing Casein phosphopeptide-amorphous calcium phosphate(CPP-ACP), fluoride varnish and low-level fluoride mouthrinse on enamel erosion induced by carbonated beverage in a short period of time. Enamel specimens were treated as follows and were then kept in artificial saliva for 24 hours followed by further processing by alternately soaking them in Cola beverage and in distilled water for 1 minute each five times. Group 1: control group (no treatment)
Group 2: tooth cream with CPP-ACP Group 3: fluoride varnish (1,000 ppm F) Group 4: low-level fluoride mouthrinse (227 ppm F) Group 5: fluoride varnish + tooth cream with CPP-ACP Group 6: low-level fluoride mouthrinse + tooth cream with CPP-ACP Microhardness and erosion depth were measured and the mineral loss of each specimen was evaluated by measuring the volumetric fluorescence change(¥ÄQ) against the stable fluorescent grid using quantitative lightinduced fluorescence(QLF). The experiment lasted for 6 days repeated each day. The results were as follows: 1. The microhardness was increased as follows: Group 1¡Â2¡Â4<6<3¡Ö5. 2. The mean erosion depth was increased as follows: Group 5¡Ö3<6<4¡Ö2¡Ö1. 3. The ¥ÄQ was increased as follows: Group 1¡Ö2¡Â4¡Â6¡Â3¡Ö5. The decrement of ¥ÄQ was similar between group 1 and 2, group 4 and 6 and group 3 and 5. 4. The ¥ÄQ showed positive correlation with microhardness (r=0.96, p<0.05), while it was negatively correlated to erosion depth (r=-0.96, p<0.05).

Å°¿öµå

Ä¡¾ÆÅ©¸²;ºÒ¼Ò ¹Ù´Ï½¬;ºÒ¼Ò ¾çÄ¡¾×;¹Ì¼¼°æµµ;ħ½Ä±íÀÌ;ºÎÇÇ Çü±¤ º¯È­(¥ÄQ)
Tooth cream;Fluoride varnish;Fluoride mouthrinse;Microhardness;Erosion depth;Volumetric fluorescence change(¥ÄQ)

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